Hyoscine Nursing Responsibilities

Generic Name: Hyoscine Butylbromide

Brand Name: Amucin, Ascopen, Buscin, Buscomed, Buscopan, Busopin, Buston, Fucon, Gascopan, Gastride, Losil, Rotomide, Scolmin, Spasmosan, Xspas

Classification: Antispasmodic, Muscle Relaxant


1. Spasms of the stomach, intestines or bile duct (gastro-intestinal tract), including those associated with irritable bowel syndrome

2. This injectable form of hyoscine may also be used before certain medical procedures (e.g., endoscopy) to relax the smooth muscle of the stomach and intestines (gastrointestinal tract).

Buscopan tablets contain the active ingredient hyoscine butylbromide, which is a type of medicine called an antispasmodic. It is used to relieve colicky abdominal pain that is caused by painful spasms in the muscles of the gastro-intestinal (GI) or genito-urinary (GU) tract.

Mechanism of Action

  • Hyoscine works by relaxing the muscle that is found in the walls of the stomach, intestines, bowel, bile duct and urinary tract. This type of muscle is called smooth muscle or involuntary muscle. It normally contracts and relaxes in response to natural body chemicals called neurotransmitters. The contractions are caused by a neurotransmitter called acetylcholine. These contractions are not under our conscious control and we are not normally aware of them. However, if the muscles go into spasm this can cause pain.
  • Hyoscine stops the spasms in the smooth muscle by preventing acetylcholine from acting on the muscle. It does this by blocking the receptors on the muscle cells that the acetylcholine would normally act on.
  • By preventing acetylcholine from acting on the muscle in the GI and GU tracts, hyoscine reduces the muscle contractions. This allows the muscle to relax and reduces the painful spasms and cramps.


  • Abnormal muscle weakness
  • Abnormally large or dilated large intestine (megacolon)
  • Rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency (Buscopan tablets contain sucrose).
  • Children under 6 years of age
  • Narrow-angle glaucoma
  • Acute hemorrhage
  • Paralytic ileus
  • Tachycardia due to cardiac insufficiency
  • Myasthenia gravis

Use in Caution in People with

  • Elderly people
  • People with a very fast heartbeat (tachycardia)
  • Heart failure
  • Overactive thyroid gland
  • People susceptible to blockages in the urinary tract and difficulty passing urine, for example men with an enlarged prostate gland
  • People susceptible to blockages in the intestines.
  • People with a high temperature (fever).
  • Pregnancy. This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than the possible risk to the foetus, particularly in the first trimester.
  • Breastfeeding. It is not known if this medicine passes into breast milk. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant.

Daisy Jane Antipuesto RN MN

Currently a Nursing Local Board Examination Reviewer. Subjects handled are Pediatric, Obstetric and Psychiatric Nursing. Previous work experiences include: Clinical instructor/lecturer, clinical coordinator (Level II), caregiver instructor/lecturer, NC2 examination reviewer and staff/clinic nurse. Areas of specialization: Emergency room, Orthopedic Ward and Delivery Room. Also an IELTS passer.

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