PIPERACILLIN SODIUM

(pi-per’a-sill-in)
Pipracil
Classifications: antiinfective; beta-lactam antibiotic; antipseudomonal penicillin
Prototype: Mezlocillin
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

• Obtain history of hypersensitivity to penicillins, cephalosporins, or other drugs prior to administration.
• Lab tests: C&S prior to first dose of the drug; start drug pending results. Periodic CBC with differential, platelet count, Hgb and Hct, and serum electrolytes.
• Monitor for hypersensitivity response; discontinue drug and notify physician if allergic response noted.
• Lab tests: Periodic CBC with differential, platelet count, Hgb and Hct, and serum electrolytes.
• Monitor for hemorrhagic manifestations because high doses may induce coagulation abnormalities.

Patient & Family Education

• Report significant, unexplained diarrhea.
• Withhold drug and report to physician if signs of an allergic reaction develop (e.g., itching, rash, hives).
• Do not breast feed while taking this drug without consulting physician.

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