PIPERACILLIN SODIUM

(pi-per’a-sill-in)
Pipracil
Classifications:
antiinfective; beta-lactam antibiotic; antipseudomonal penicillin
Prototype: Mezlocillin
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

  • Obtain history of hypersensitivity to penicillins, cephalosporins, or other drugs prior to administration.
  • Lab tests: C&S prior to first dose of the drug; start drug pending results. Periodic CBC with differential, platelet count, Hgb and Hct, and serum electrolytes.
  • Monitor for hypersensitivity response; discontinue drug and notify physician if allergic response noted.
  • Lab tests: Periodic CBC with differential, platelet count, Hgb and Hct, and serum electrolytes.
  • Monitor for hemorrhagic manifestations because high doses may induce coagulation abnormalities.

Patient & Family Education

  • Report significant, unexplained diarrhea.
  • Withhold drug and report to physician if signs of an allergic reaction develop (e.g., itching, rash, hives).
  • Do not breast feed while taking this drug without consulting physician.

 

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