LOPERAMIDE

(loe-per’a-mide)
Imodium, Imodium AD, Kaopectate III, Maalox Anti-diarrheal, Pepto Diarrhea Control
Classifications:
gastrointestinal agent; antidiarrheal
Prototype: Diphenoxylate HCl with atropine sulfate
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

  • Monitor therapeutic effectiveness. Chronic diarrhea usually responds within 10 d. If improvement does not occur within this time, it is unlikely that symptoms will be controlled by further administration.
  • Discontinue if there is no improvement after 48 h of therapy for acute diarrhea.
  • Monitor fluid and electrolyte balance.
  • Notify physician promptly if the patient with ulcerative colitis develops abdominal distention or other GI symptoms (possible signs of potentially fatal toxic megacolon).

Patient & Family Education

  • Notify physician if diarrhea does not stop in a few days or if abdominal pain, distension, or fever develops.
  • Record number and consistency of stools.
  • Do not drive or engage in other potentially hazardous activities until response to drug is known.
  • Do not take alcohol and other CNS depressants concomitantly unless otherwise advised by physician; may enhance drowsiness.
  • Learn measures to relieve dry mouth; rinse mouth frequently with water, suck hard candy.
  • Do not breast feed while taking this drug without consulting physician.

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