Classifications: central nervous system agent, analgesic, nsaid, cyclooxygenase-2 inhibitor, antipyretic
Pregnancy Category: C first and second trimesters; D third trimester
Assessment & Drug Effects
- Therapeutic effectiveness is indicated by relief of joint pain.
- Lab tests: Periodically monitor Hct and Hgb, liver functions, BUN and creatinine, and serum electrolytes.
- Monitor closely lithium levels when the two drugs are given concurrently.
- Monitor closely PT/INR when used concurrently with warfarin.
- Monitor for fluid retention and edema especially in those with a history of hypertension or CHF.
Patient & Family Education
- Avoid using celecoxib during the third trimester of pregnancy.
- Promptly report any of the following: unexplained weight gain, edema, skin rash.
- Stop taking celecoxib and promptly report to physician if any of the following occurs: S&S of liver dysfunction including nausea, fatigue, lethargy, itching, jaundice, abdominal pain, and flulike symptoms; S&S of GI ulceration including black, tarry stools and upper GI distress.
- Do not breast feed while taking this drug.