Amoxil, Apo-Amoxi , Larotid, Novamoxin, Polymox, Sumox, Trimox, Utimox, Wymox, DisperMox
antiinfective; antibiotic; aminopenicillin
Prototype: Ampicillin
Pregnancy Category: B


Assessment & Drug Effects

  • Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy.
  • Lab tests: Baseline C&S tests prior to initiation of therapy, start drug pending results; periodic assessments of renal, hepatic, and hematologic functions should be made during prolonged therapy.
  • Monitor for S&S of an urticarial rash (usually occurring within a few days after start of drug) suggestive of a hypersensitivity reaction. If it occurs, look for other signs of hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately.
  • Report onset of generalized, erythematous, maculopapular rash (ampicillin rash) to physician. Ampicillin rash is not due to hypersensitivity; however, hypersensitivity should be ruled out.
  • Closely monitor diarrhea to rule out pseudomembranous colitis.

Patient & Family Education

  • Take drug around the clock, do not miss a dose, and continue therapy until all medication is taken, unless otherwise directed by physician.
  • Report onset of diarrhea and other possible symptoms of superinfection to physician (see Appendix F).
  • Do not breast feed while taking this drug without consulting physician.

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