cardiovascular agent; calcium channel blocker; antihypertensive agent
Prototype: Nifedipine
Pregnancy Category: C


Assessment & Drug Effects

  • Monitor BP for therapeutic effectiveness. BP reduction is greatest after peak levels of amlodipine are achieved 6–9 h following oral doses.
  • Monitor for S&S of dose-related peripheral or facial edema that may not be accompanied by weight gain; rarely, severe edema may cause discontinuation of drug.
  • Monitor BP with postural changes. Report postural hypotension. Monitor more frequently when additional antihypertensives or diuretics are added.
  • Monitor heart rate; dose-related palpitations (more common in women) may occur.

Patient & Family Education

  • Report significant swelling of face or extremities.
  • Take care to have support when standing & walking due to possible dose-related light-headedness/dizziness.
  • Report shortness of breath, palpitations, irregular heartbeat, nausea, or constipation to physician.
  • Do not breast feed while taking this drug without consulting physician.

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