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Pathophysiology of Asthma

August 27, 2008 by Admin · 12 Comments  · Email This Post Email This Post · Print This Post Print This Post

1. An asthma attack may occur spontaneously or in response to a trigger. Either way, the attack progresses in the following manner:

  • There is an initial release of inflammatory mediators from bronchial mast cells, epithelial cells, and macrophages, followed by activation of other inflammatory cells
  • Alteration of autonomic neural control of airway tone and epithelial integrity occur and the increased responsiveness in airways smooth muscle results in clinical manifestations (e.g. wheezing and dyspnea)

2. Three events contribute to clinical manifestations

  • Bronchial spasm
  • Inflammation and edema of the mucosa
  • Production of thick mucus, which results in increased airway resistance, premature closure of airways, hyperinflation, increased work of breathing, and impaired gas exchange

3. If not treated promptly, status asthmaticus – an acute, severe, prolonged asthma attack that is unresponsive to the usual treatment – may occur, requiring hospitalization.

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Comments

12 Responses to “Pathophysiology of Asthma”
  1. yhan says:
    March 7, 2010 at 8:02 pm

    thank ntulungan nio ko sa project nmen na case study,,wla na pba ibng example ng nursing care plan i nid 2 for bronchial asthma,,

    Reply
  2. jhen says:
    February 19, 2010 at 11:40 am

    case study nga po about AGE?

    Reply
  3. monica says:
    January 7, 2010 at 12:28 pm

    ncp nga po ng Acute Gastro enteritis..tnx

    Reply
  4. dessa says:
    January 4, 2010 at 11:31 am

    thank you po!!!!! nakaka2long pu talaga website nyu….

    thanks ulet….

    Reply
  5. JACQUE says:
    July 20, 2009 at 6:41 pm

    thanks a lot for the information.. you are a great help! :D God bless you all :D

    Reply
  6. vaney says:
    April 25, 2009 at 6:16 pm

    i need a case study about bronchial asthma acute excavation..
    please help me ineed it badly………tnx

    Reply
  7. zei says:
    March 4, 2009 at 8:31 pm

    thanx a lot for the explanation!!!

    Reply
  8. Jenny Clarin says:
    February 25, 2009 at 9:34 pm

    Hello a gain…..
    I need a case study about Acute Gastro enteritis..
    Help me please
    Im waiting for your help…
    please …..

    Ineed it for our revalida….

    thanks…
    Jhen

    Reply
  9. Marie Rose Campana says:
    November 2, 2008 at 10:50 am

    Thanks a lot for the effort for giving us information, to help us in our studies. You are such a big help for us, students….

    Reply

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  1. Asthma Case Study | Nursing Crib says:
    August 27, 2008 at 3:00 pm

    [...] PATHOPHYSIOLOGY: [...]

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