IBUPROFEN

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(eye-byoo’proe-fen)
Advil, Amersol , Children’s Motrin, Haltran, Ibuprin, Junior Strength Motrin Caplets, Medipren, Motrin, Nuprin, Pediaprofen, Pamprin-IB, Rufen, Trendar
Classifications: central nervous system agent; nsaid (cox-1); analgesic; antipyretic
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

• Monitor for therapeutic effectiveness. Optimum response generally occurs within 2 wk (e.g., relief of pain, stiffness, or swelling; or improved joint flexion and strength).
• Observe patients with history of cardiac decompensation closely for evidence of fluid retention and edema.
• Lab tests: Baseline and periodic evaluations of Hgb, renal and hepatic function, and auditory and ophthalmologic examinations are recommended in patients receiving prolonged or high-dose therapy.
• Monitor for GI distress and S&S of GI bleeding.
• Note: Symptoms of acute toxicity in children include apnea, cyanosis, response only to painful stimuli, dizziness, and nystagmus.

Patient & Family Education

• Notify physician immediately of passage of dark tarry stools, "coffee ground" emesis, frankly bloody emesis, or other GI distress, as well as blood or protein in urine, and onset of skin rash, pruritus, jaundice.
• Do not drive or engage in other potentially hazardous activities until response to the drug is known.
• Do not self-medicate with ibuprofen if taking prescribed drugs or being treated for a serious condition without consulting physician.
• Do not take aspirin concurrently with ibuprofen.
• Avoid alcohol and NSAIDs unless otherwise advised by physician. Concurrent use may increase risk of GI ulceration and bleeding tendencies.
• Do not breast feed while taking this drug without consulting physician.

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• ENOXAPARIN (e-nox’a-pa-rin) Lovenox Classifications: blood formers, coagulators, and anticoagulants; low molecular weight heparin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Lab tests: Baseline coagulation studies; periodic CBC, platelet count, urine and stool for occult blood. Monitor platelet count closely. Withhold drug and notify physician if platelet
• DICLOFENAC SODIUM (di-klo’fen-ak) Voltaren, Voltaren-XR, Solaraze DICLOFENAC POTASSIUM Cataflam Classifications: central nervous system agent; analgesic, antipyretic; nsaid Prototype: Ibuprofen Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Monitor for therapeutic effectiveness. Up to 3 wks may be needed for beneficial effects with rheumatoid arthritis or osteoarthritis. Lab tests: Periodic liver function,
• MEFENAMIC ACID (me-fe-nam’ik) Ponstan, Ponstel Classifications: central nervous system agent; analgesic; nsaid; antipyretic Prototype: Ibuprofen Pregnancy Category: C NURSING IMPLICATIONS Assessment & Drug Effects Assess patients who develop severe diarrhea and vomiting for dehydration and electrolyte imbalance. Lab tests: With long-term therapy (not recommended) obtain periodic complete blood counts, Hct and
• AMPICILLIN SODIUM AND SULBACTAM SODIUM (am-pi-sill’in/sul-bak’tam) Unasyn Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results. Report promptly unexplained
• ESOMEPRAZOLE MAGNESIUM (e-so-me’pra-zole) Nexium Classifications: gastrointestinal agent; proton pump inhibitor Prototype: Omeprazole Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Monitor for S&S of adverse CNS effects (vertigo, agitation, depression) especially in severely ill patients. Monitor phenytoin levels with concurrent use. Monitor INR/PT with concurrent