DOBUTAMINE HYDROCHLORIDE

(doe-byoo’ta-meen)
Dobutrex
Classifications: autonomic nervous system agent; beta-adrenergic agonist; catecholamine
Prototype: Isoproterenol
Pregnancy Category: C

NURSING IMPLICATIONS

Assessment & Drug Effects

• Correct hypovolemia by administration of appropriate volume expanders prior to initiation of therapy.
• Monitor therapeutic effectiveness. At any given dosage level, drug takes 10–20 min to produce peak effects.
• Monitor ECG and BP continuously during administration.
• Note: Marked increases in blood pressure (systolic pressure is the most likely to be affected) and heart rate, or the appearance of arrhythmias or other adverse cardiac effects are usually reversed promptly by reduction in dosage.
• Observe patients with preexisting hypertension closely for exaggerated pressor response.
• Note: Tolerance has been observed with continuous or prolonged infusions; adverse reactions are no different than those seen with shorter infusions.
• Monitor I&O ratio and pattern. Urine output and sodium excretion generally increase because of improved cardiac output and renal perfusion.

Patient & Family Education

• Report anginal pain to physician promptly.
• Do not breast feed while taking this drug without consulting physician.

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