Gather equipment. Check medication order against original physician’s order according to agency policy.
Perform hand hygiene.
If necessary, remove metal cap that protects rubber stopper on each vial.
If insulin is a suspension (NPH [neural protamine hagedorn], lente), roll and agitate the vial to mix it well.
Cleanse rubber tops with alcohol swabs.
Remove cap from needle,. Inject air into the modified insulin preparation (e.g., NPH insulin). Touch plunger at knob only. Use an amount of medication to be withdrawn. Do not allow needle to touch medication in the vial. Remove needle.
Inject air into the clear insulin without additional protein (eg, regular insulin). Use an amount of air equal to the amount of medication to be withdrawn.
Invert the vial of clear insulin and aspirate the amount prescribed. Remove needle from vial.
Cleanse rubber top of the modified insulin vial. Insert needle into this vial, invert it, and withdraw medication. Carefully replace cap over needle.