CEFUROXIME SODIUM

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(se-fyoor-ox’eem)
Kefurox, Zinacef
CEFUROXIME AXETIL
Ceftin
Classifications: antiinfective; antibiotic; second-generation cephalosporin
Prototype: Cefonicid sodium
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

• Determine history of hypersensitivity reactions to cephalosporins, penicillins, and history of allergies, particularly to drugs, before therapy is initiated.
• Lab tests: Perform culture and sensitivity tests before initiation of therapy and periodically during therapy if indicated. Therapy may be instituted pending test results. Monitor periodically BUN and creatinine clearance.
• Inspect IM and IV injection sites frequently for signs of phlebitis.
• Report onset of loose stools or diarrhea. Although pseudomembranous colitis (see Signs & Symptoms, Appendix F) rarely occurs, this potentially life-threatening complication should be ruled out as the cause of diarrhea during and after antibiotic therapy.
• Monitor for manifestations of hypersensitivity (see Appendix F). Discontinue drug and report their appearance promptly.
• Monitor I&O rates and pattern: Especially important in severely ill patients receiving high doses. Report any significant changes.

Patient & Family Education

• Report loose stools or diarrhea promptly.
• Report any signs or symptoms of hypersensitivity (see Appendix F).
• Do not breast feed while taking this drug.

Other Nursing Articles you may want to look at:

• CEPHALEXIN (sef-a-lex’in) Cefanex, Ceporex_A, Keflet, Keflex, Keftab, Novolexin_A Classifications: antiinfective; antibiotic; first-generation cephalosporin Prototype: Cefazolin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine history of hypersensitivity reactions to cephalosporins and penicillin and history of other drug allergies before therapy is initiated. Lab tests: Evaluate renal and hepatic
• MEROPENEM (mer-o’pe-nem) Merrem Classifications: antiinfective; carbapenem antibiotic Prototype: Imipenem Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Lab tests: Perform C&S tests prior to therapy. Monitor periodically liver and kidney function. Determine history of hypersensitivity reactions to other beta-lactams, cephalosporins, penicillins, or other drugs. Discontinue drug and
• AZITHROMYCIN (a-zi-thro-mye’sin) Zithromax Classifications: antiinfective; macrolide antibiotic Prototype: Erythromycin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Monitor for and report loose stools or diarrhea, since pseudomembranous colitis (see Appendix F) must be ruled out. Monitor PT and INR closely with concurrent warfarin use. Patient & Family Education Direct sunlight
• AMPICILLIN SODIUM AND SULBACTAM SODIUM (am-pi-sill’in/sul-bak’tam) Unasyn Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results. Report promptly unexplained
• AMOXICILLIN (a-mox-i-sill’in) Amoxil, Apo-Amoxi , Larotid, Novamoxin, Polymox, Sumox, Trimox, Utimox, Wymox, DisperMox Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of