AMPICILLIN SODIUM AND SULBACTAM SODIUM

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(am-pi-sill’in/sul-bak’tam)
Unasyn
Classifications: antiinfective; antibiotic; aminopenicillin
Prototype: Ampicillin
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

• Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy.
• Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results.
• Report promptly unexplained bleeding (e.g., epistaxis, purpura, ecchymoses).
• Monitor patient carefully during the first 30 min after initiation of IV therapy for signs of hypersensitivity and anaphylactoid reaction (see Appendix F). Serious anaphylactoid reactions require immediate use of emergency drugs and airway management.
• Observe for and report symptoms of superinfections (see Appendix F). Withhold drug and notify physician.
• Monitor I&O ratio and pattern. Report dysuria, urine retention, and hematuria.

Patient & Family Education

• Report chills, wheezing, pruritus (itching), respiratory distress, or palpitations to physician immediately.
• Do not breast feed while taking this drug without consulting physician.

 

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• CEFUROXIME SODIUM (se-fyoor-ox’eem) Kefurox, Zinacef CEFUROXIME AXETIL Ceftin Classifications: antiinfective; antibiotic; second-generation cephalosporin Prototype: Cefonicid sodium Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine history of hypersensitivity reactions to cephalosporins, penicillins, and history of allergies, particularly to drugs, before therapy is initiated. Lab tests: Perform culture and sensitivity tests before
• CLOXACILLIN, SODIUM (klox-a-sill’in) Apo-Cloxi , Cloxapen, Cloxilean, Novocloxin , Orbenin, Tegopen Classifications: antiinfective; antibiotic, natural penicillin; beta-lactam Prototype: Penicillin G Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous exposure and sensitivity to penicillins and cephalosporins and other allergic reactions of any kind before treatment is initiated. Monitor for S&S of
• CEPHALEXIN (sef-a-lex’in) Cefanex, Ceporex_A, Keflet, Keflex, Keftab, Novolexin_A Classifications: antiinfective; antibiotic; first-generation cephalosporin Prototype: Cefazolin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine history of hypersensitivity reactions to cephalosporins and penicillin and history of other drug allergies before therapy is initiated. Lab tests: Evaluate renal and hepatic