AMOXICILLIN
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(a-mox-i-sill’in)
Amoxil, Apo-Amoxi , Larotid, Novamoxin, Polymox, Sumox, Trimox, Utimox, Wymox, DisperMox
Classifications: antiinfective; antibiotic; aminopenicillin
Prototype: Ampicillin
Pregnancy Category: B
NURSING IMPLICATIONS
Assessment & Drug Effects
- Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy.
- Lab tests: Baseline C&S tests prior to initiation of therapy, start drug pending results; periodic assessments of renal, hepatic, and hematologic functions should be made during prolonged therapy.
- Monitor for S&S of an urticarial rash (usually occurring within a few days after start of drug) suggestive of a hypersensitivity reaction. If it occurs, look for other signs of hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately.
- Report onset of generalized, erythematous, maculopapular rash (ampicillin rash) to physician. Ampicillin rash is not due to hypersensitivity; however, hypersensitivity should be ruled out.
- Closely monitor diarrhea to rule out pseudomembranous colitis.
Patient & Family Education
- Take drug around the clock, do not miss a dose, and continue therapy until all medication is taken, unless otherwise directed by physician.
- Report onset of diarrhea and other possible symptoms of superinfection to physician (see Appendix F).
- Do not breast feed while taking this drug without consulting physician.
Other Nursing Articles you may want to look at:
- AMOXICILLIN AND CLAVULANATE POTASSIUM (a-mox-i-sill’in) Augmentin, Augmentin-ES600, Augmentin XR, Clavulin Classifications: antiinfective; beta-lactam antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending
- AMPICILLIN SODIUM AND SULBACTAM SODIUM (am-pi-sill’in/sul-bak’tam) Unasyn Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results. Report promptly unexplained
- PIPERACILLIN SODIUM (pi-per’a-sill-in) Pipracil Classifications: antiinfective; beta-lactam antibiotic; antipseudomonal penicillin Prototype: Mezlocillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Obtain history of hypersensitivity to penicillins, cephalosporins, or other drugs prior to administration. Lab tests: C&S prior to first dose of the drug; start drug pending results. Periodic CBC
- CEFUROXIME SODIUM (se-fyoor-ox’eem) Kefurox, Zinacef CEFUROXIME AXETIL Ceftin Classifications: antiinfective; antibiotic; second-generation cephalosporin Prototype: Cefonicid sodium Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine history of hypersensitivity reactions to cephalosporins, penicillins, and history of allergies, particularly to drugs, before therapy is initiated. Lab tests: Perform culture and sensitivity tests before
- MEROPENEM (mer-o’pe-nem) Merrem Classifications: antiinfective; carbapenem antibiotic Prototype: Imipenem Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Lab tests: Perform C&S tests prior to therapy. Monitor periodically liver and kidney function. Determine history of hypersensitivity reactions to other beta-lactams, cephalosporins, penicillins, or other drugs. Discontinue drug and



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