AMOXICILLIN AND CLAVULANATE POTASSIUM

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(a-mox-i-sill’in)
Augmentin, Augmentin-ES600, Augmentin XR, Clavulin 
Classifications: antiinfective; beta-lactam antibiotic; aminopenicillin
Prototype: Ampicillin
Pregnancy Category: B

NURSING IMPLICATIONS

Assessment & Drug Effects

• Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy.
• Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results.
• Monitor for S&S of an urticarial rash (usually occurring within a few days after start of drug) suggestive of a hypersensitivity reaction. If it occurs, look for other signs of hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately.
• Note: Generalized, erythematous, maculopapular rash (ampicillin rash) is not due to hypersensitivity. It is usually mild, but can be severe. Report onset of rash to physician, since hypersensitivity should be ruled out.

Patient & Family Education

• Female patients should report onset of symptoms of Candidal vaginitis (e.g., moderate amount of white, cheesy, nonodorous vaginal discharge; vaginal inflammation and itching; vulvar excoriation, inflammation, burning, itching). Therapy may have to be discontinued.
• Note: Use Clinistix or TesTape when monitoring urinary glucose to avoid false readings with diabetes mellitus.
• Do not breast feed while taking this drug without consulting physician.

Other Nursing Articles you may want to look at:

• AMOXICILLIN (a-mox-i-sill’in) Amoxil, Apo-Amoxi , Larotid, Novamoxin, Polymox, Sumox, Trimox, Utimox, Wymox, DisperMox Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of
• AMPICILLIN SODIUM AND SULBACTAM SODIUM (am-pi-sill’in/sul-bak’tam) Unasyn Classifications: antiinfective; antibiotic; aminopenicillin Prototype: Ampicillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending results. Report promptly unexplained
• PIPERACILLIN SODIUM (pi-per’a-sill-in) Pipracil Classifications: antiinfective; beta-lactam antibiotic; antipseudomonal penicillin Prototype: Mezlocillin Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Obtain history of hypersensitivity to penicillins, cephalosporins, or other drugs prior to administration. Lab tests: C&S prior to first dose of the drug; start drug pending results. Periodic CBC
• MEROPENEM (mer-o’pe-nem) Merrem Classifications: antiinfective; carbapenem antibiotic Prototype: Imipenem Pregnancy Category: B NURSING IMPLICATIONS Assessment & Drug Effects Lab tests: Perform C&S tests prior to therapy. Monitor periodically liver and kidney function. Determine history of hypersensitivity reactions to other beta-lactams, cephalosporins, penicillins, or other drugs. Discontinue drug and
• LEVOFLOXACIN (lev-o-flox’a-sin) Levaquin, Iquix, Quixin Classifications: antiinfective; antibiotic; quinolone Prototype: Ciprofloxacin Pregnancy Category: C NURSING IMPLICATIONS Assessment & Drug Effects Lab tests: Do C&S test prior to beginning therapy and periodically. Withhold therapy and report to physician immediately any of the following: Skin rash or other signs of a